It's the return of one of Spidey’s oldest foes, Doctor Octopus, the two archenemies set into motion a gut-wrenching series of events leading to the death of Captain George Stacy. Ally to Spider-Man and father to Peter Parker’s ladylove, Gwen, Captain Stacy’s death marks Spidey for murder and pits the entire city against him. Now with hero, villain and even the man-on-the-street after him, there’s no moment for rest for the ol’ web-slinger as he wriggles his way through threats from the X-Men’s Iceman to the politicking Sam Bullit and former friend the Prowler. And it all leads into one of the landmark moments of Marvel history, when Peter Parker’s best friend, Harry Osborn, was revealed to be a drug addict.