Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations

By including clinical models of agonism, indirect drug effects, tolerance, signal transduction, and disease progression, author Sara Rosenbaum has created a work that stands out among introductory-level textbooks in this area.You'll find several features throughout the text to help you better understand and apply key concepts:

• Three fictitious drugs are used throughout the text to progressively illustrate the development and application of pharmacokinetic and pharmacodynamic principles

• Exercises at the end of each chapter reinforce the concepts and provide the opportunity to perform and solve common dosing problems

• Detailed instructions let you create custom Excel worksheets to perform simple pharmacokinetic analyses

Because this is an introductory textbook, the material is presented as simply as possible. As a result, you'll find it easy to gain an accurate, working knowledge of all the core principles, apply them to optimize dosing regimens, and evaluate the clinical pharmacokinetic and pharmacodynamic literature.