1349: England. Pestilence rages across the land, leaving death and fear in its wake. A young woman and skilled healer, Alyse Elsey, loses her husband, children and friends to the fearsome disease, despite her care and knowledge. Left to care for her best friend's son, Harold, Alyse sets out on a perilous journey to the priory in Norwich, determined to find a safe haven with Harold's uncle, a young monk at the priory. But Norwich has also been consumed by the pestilence. In a world filled with superstition, religious fervor and fear of the unknown, Alyse must find a way to go on without her dead and embrace the love and hope of the living.