Written by a pioneering leader in the development of vitreoretinal surgical techniques and instruments, Vitreous Microsurgery is a comprehensive how-to guide to all vitreoretinal procedures. This thoroughly updated Fifth Edition describes many new techniques and refinements of established procedures. More than 170 three-dimensional full-color illustrations—many by the Charles Retina Institute's resident medical artist, Byron Wood—enable surgeons to clearly visualize the techniques. This edition has new chapters on the Constellation vitrectomy system, uveitis, retinal complications of permanent keratoprosthesis, and anti-VEGF therapy and completely rewritten chapters on anesthesia and on retinopathy of prematurity. All illustrations have been updated, the majority to a 25-gauge approach instead of 20-gauge, and many new illustrations have been added. Many techniques and parameters unique to 25-gauge sutureless vitrectomy are discussed in detail.