Three prominent world figureheads disappear following The World Summit in Kuala Lumpur. The following day, US President John Remy is found dead of a heart attack in his hotel room.
Meanwhile, two friends on a road trip across North America come to the aid of a mysterious woman they find washed up and battered on the banks of the Colorado River. Somehow, all the events are linked.
Choosing to help her plunges them into a nightmarish race across the globe, for she holds a secret that defies all we know about human evolution. Pursued by a deadly force intent on stopping them, they must recover a relic so ancient it's fallen into legend. A relic that will not only save them, but the whole of humanity.